The nervous system layer ofof preventive healthcare
Our CloudANS™ platform transforms everyday wearables into continuous autonomic nervous system (ANS) monitors, revealing system-level dysfunction before symptoms and enabling personalized, longitudinal care for complex conditions involving women’s health, Long COVID, autoimmune disorders, and others, where labs often fall short.
The missing puzzle piece
The autonomic nervous system (ANS) is the body’s real-time operating system, regulating heart, lungs, hormones, digestion, immunity, and energy without conscious effort. It has two branches: the sympathetic system, which supports activity and stress response, and the parasympathetic system, which supports rest, recovery, and repair. When this balance is disrupted, chronic disease often begins long before abnormalities appear in labs or scans. CloudANS™ measures both ANS branches directly and independently, revealing upstream dysfunction. Traditional models focus on surface symptoms. We read the operating system itself.
Upstream detection
vs. downstream response
The ANS picks up the first signal of disease before labs or imaging changes.
Root-cause treatment
vs. symptom suppression
Fix the control-system imbalance, don't mask downstream effects.
Continuous 1:1 personalization
vs. static population averages
Each ANS is a unique physiological fingerprint, enabling true individualized care.
Autonomic Nervous System
Body's Real-Time Operating System
A clinical dashboard for homeostasis
For thousands of years, doctors and healers across civilizations spoke of one unifying principle: balance in the body. Health, they believed, was not simply the absence of disease, but the presence of harmony — between fluids, energies, or forces that sustained life.
The Greeks described balance in terms of the four humors — blood, phlegm, yellow bile, and black bile. In India, Ayurveda spoke of the three doshas — Vata, Pitta, and Kapha. In China, medicine revolved around the interplay of yin and yang, with smooth flow of qi keeping the body in rhythm. Though their languages differed, the insight was universal: imbalance leads to disease, and restoration of balance is the essence of healing.
Today, modern biology has given this ancient wisdom a new name: homeostasis. At every moment, our bodies are adjusting — heart rate, blood pressure, temperature, hormone levels, digestion, immunity — to keep us alive and well in a changing environment. The engine behind this constant fine-tuning is the autonomic nervous system (ANS) — the body’s real-time operating system.
CloudANS provides a clinical dashboard for homeostasis and actionable insights on how to maintain balance in the body in order to prevent disease and boost longevity.
Homeostasis = Balanced ANS = Diagonal
AAD: Advanced Autonomic Dysfunction • DAN: Diabetic Autonomic Neuropathy
CAN: Cardiovascular Autonomic Neuropathy
The $550 billion crisis of "normal labs, sick patients"
Avoidable ER visits, hospitalizations, tests and treatments in America cost $550 billion each year. Existing diagnostics see organs, not control systems. Dysfunction spreads across multiple systems when the ANS is out of balance leaving patients seeing specialist after specialist.
Traditional diagnostics miss the earliest and most critical signal: autonomic imbalance.
Blood Panels & Scans
Miss early signals
ANS Dysfunction
Goes undetected
Unresolved Disease Loop
Conditions worsen
Autonomic Testing
Finally reveals the root cause and provides a clear path forward
The Most Complete Autonomic Intelligence Platform Ever Built
CloudANS™ brings clinical-grade autonomic testing and interpretation to wearables using the validated autonomic protocol used across more than 1 million patients and 200 clinical studies. CloudANS™ is made of five integrated components.
Patent-Pending Measurement
Wearable heartbeats become true autonomic signals
Our proprietary AI-based spectral separation engine decodes sympathetic and parasympathetic activity independently using only heartbeat interval data.
- Compatible with Apple Watch, Oura, Whoop, Garmin
- No new hardware is required
- Global scale using the existing wearable footprint
Cloud-Based Diagnostic
Validated protocol delivered through the cloud
Guided by our CMO who helped launch the original FDA-approved ANS diagnostic in 2006, CloudANS™ produces diagnostic-quality autonomic profiles from consumer wearables.
- Sympathetic activity
- Parasympathetic activity
- Autonomic balance signatures
- Time-based reactivity profiles
CAJAL
The First AI Model for the Nervous System
Trained on the world’s largest FDA-grade autonomic dataset, exclusive to us, CAJAL predicts disease onset, identifies flare states, and adapts insights to each user’s unique physiology.
- 20-year clinical foundation
- 1M+ patients
- 3M+ tests
Clinical Decision Support (CDS)
More information for difficult-to-manage patients
The CDS gives clinicians structured autonomic insights that identify imbalance, detect at risk patients, and track therapy response over time. Our CDS stays within FDA guidance, ensuring that clinicians make all diagnostic and treatment decisions.
- Autonomic imbalance signatures
- At-risk patient detection
- Therapy-response tracking
- Stress and recovery analysis
CloudANS™ SDK
Autonomic intelligence inside any digital health product
The SDK provides real-time autonomic metrics, personalized insights, trend analysis, alerts, and cohort intelligence for preventive care, women’s health, mental health, chronic care, performance, and longevity.
- Integrate directly into your app
- Retention lift + premium membership tier
- New revenue stream targeting 100M+ Americans with complex disease
- Deploy in days
Why Wearables Need Direct Autonomic Intelligence
For almost 30 years, heart rate variability (HRV) has been the go-to proxy for stress, recovery, and resilience across wearables because it was the best tool available. HRV however is not an autonomic measure. HRV cannot separate sympathetic and parasympathetic activity and breaks down in chronic illness. CloudANS™ solves this.
HRV Limitations
- HRV is indirect. HF reflects breathing-related variability, often assumed to represent parasympathetic activity. LF reflects mixed signals, not pure sympathetic activity.
- HRV requires controlled breathing and stable conditions.
- HRV often appears normal in Long COVID, POTS, autoimmune disease, anxiety, perimenopause, and chronic fatigue despite dysfunction.
- HRV cannot isolate autonomic branches or support root-cause analysis.
The CloudANS™ Advantage
- True sympathetic and parasympathetic separation
- Cloud-delivered autonomic testing
- Continuous monitoring through wearables
- Diagnostic-grade interpretation powered by CAJAL
- Actionable insights for clinicians and digital health platforms
A Complete Nervous System Layer for Digital Health
CloudANS™ supports both patient experience and clinician workflows while staying fully compliant with FDA guidance.
Patient-Facing Test and Insights
MIND BODY WELLNESS GUIDANCE
- 10-minute ANS test
- Autonomic Balance over time
- Stress and recovery signatures
- Patterns associated with system-level strain
- Lifestyle, sleep, hydration, breathing, and exercise guidance
The Foundation for Autonomic First Healthcare
Digital health platforms use CloudANS™ to:
Detect dysfunction before symptoms or vitals change
Support women’s health with autonomic hormone pattern detection
Quantify mental health physiology
Identify flare states in chronic illness
Personalize recovery and resilience
Transform wearables into preventive care systems
"This is the nervous system layer of modern healthcare."
Dr. Ramesh Adiraju, MD, FACC
Meet Our Chief Medical Officer
Dr. Ramesh Adiraju, MD, FACC
A board-certified cardiologist and one of the world’s leading autonomic physicians, Dr. Adiraju has done clinical research for more than twenty years at the Dysautonomia Research Institute, a resource referenced by organizations such as Mayo Clinic, the University of Pennsylvania Medical School, and Vanderbilt. Dr. Adiraju helped lead the clinical launch of the first FDA-approved ANS diagnostic in 2006 and has treated thousands of patients with complex autonomic disorders.
Partner with Autonomic Health
CloudANS™ is now available for SDK integrations, pilots, and early-access partnerships with: